Here is a list of common used input options. For most of these options, the option groups (in:path etc) do not need to be given.
Misc
-in:ignore_unrecognized_res Do not abort if unknown residues are found in PDB file; instead, ignore them.
default='false' [Boolean].
-in:ignore_waters Ignore only WAT water molecules. Default=false. [Boolean].
-in:path:database Database file input search paths.
If the database option is not given or the database is not found,
the ROSETTA3_DB environment variable is tried [PathVector]
-in:file:residue_type_set ResidueTypeSet for input files', default = 'fa_standard. [String]
Common PDB Input File Flags
-in:file:s Name(s) of single PDB file(s) to process. [FileVector]
-in:file:l File(s) containing list(s) of PDB files to process. [FileVector]
-in:path Paths to search for input files.
Useful in combination with PDB lists that do not have full paths. [FileVector]
-in:file:native Native PDB filename. [File]
-in:file:native_exclude_res Residue numbers to be excluded from RMS calculation. [IntegerVector]
-in:file:fullatom Enable full-atom input of PDB or centroid structures.
Usually not needed for already full-atom PDB structures [Boolean]
-in:file:centroid_input Enable centroid inputs of PDBs. default = 'false' [Boolean]
-in:auto_setup_metals Enable automatic setup of covalent bonds to metal ions and appropriate
constraints on PDB import.
Relational Database Input
See here for more info
-in:use_database Indicate that structures should be read from the given database
-in:select_structures_from_database An sql query to select which structures should be extracted.
ex: "SELECT tag FROM structures WHERE tag = '7rsa';"
Fragment and Sequence Input File Flags
-in:file:fasta Fasta-formatted sequence file. [FileVector]
-in:file:frag3 Fragments file with residue length of 3 [String]
-in:file:frag9 Fragments file with residue length of 9 [String]
Silent Input File Flags
-in:file:silent Silent input filename(s). [FileVector]
-in:file:silent_list Silent input filename list(s) - like -l is to -s. [FileVector]
-in:file:silent_optH Call optH when reading a silent file. [Boolean]
-in:file:silent_structure_type Type of SilentStruct object to use in silent-file input'.
Default='protein', [String]
-in:file:silent_read_through_errors Try to salvage damaged silent files
-in:file:silent_score_prefix Prefix that is appended to all scores read in from a silent-file',
default='' [String]
Scoring
-in:file:repair_sidechains Attempt a repack/minmize to repair sidechain problems.
Such as proline geometry and his tautomerization' default = 'false'
[Boolean]