Changes in version 3.0 of NCBI ASN.1 specification these change the asn.1 files and their object loaders. NOTE: simple.c changes also general.asn - 1) Int-fuzz A) added "circle" to indicate artificial break in a location that spans origin of a circular sequence B) added "alt" for a series of alternate positions biblio.asn - 1) Cit-pat adapted to include additional fields A) Cit-pat.class changed from VisibleString to SEQUENCE OF VisibleString. Since class was not formally populated this destructive change should not be a problem. B) new fields assignees, priority, abstract 2) Affil - added email, fax, phone 3) Cit-sub - added descr for author to describe any changes for the public added date, and made imprint optional. Imprint will go away and be replaced by just a date. 4) retraction/erratum notice added to imprint. CitRetract ::= SEQUENCE { type ENUMERATED { -- retraction of an entry retracted (1) , -- this citation retracted notice (2) , -- this citation is a retraction notice in-error (3) , -- an erratum was published about this erratum (4) } , -- this is a published erratum exp VisibleString OPTIONAL } -- citation and/or explanation 5) added part-supi on imprint for part/supplement on issue old part-sup now specificially for volume seq.asn - 1) Seq-descr redefined as SET OF Seqdesc, with Seqdesc being a CHOICE of the old elements of Seqdesc, Seqdesc.E This enables single elements to be named for various tools. 2) GIBB-mod, GIBB-mol, GIBB-method, org expanded and consolidated into MolInfo and new Org-ref. These old descriptors will be removed with the next spec. 3) Seq-inst added type "delta", Delta-seq, Seq-literal, for constructing a sequence by changes (deltas) to another. 4) Seq-annot changed "id" to use Annot-id changed "db" to represent a source db changed "name" to represent a source name changed "desc" from VisibleString to Annot-descr for separate seq-annots to have comments, titles, publications, etc. 5) Added BioSource and MolInfo to Seq-descr seqblock.asn - 1) Added divisions est, pat, sts to EMBL block seqfeat.asn - 1) added sites signal-peptide (23) , transit_peptide (24) , transmembrane-region (25) 2) expanded Org-ref 3) added processing status to Prot-ref processed ENUMERATED { -- processing status not-set (0) , preprotein (1) , mature (2) } DEFAULT not-set } 4) added BioSource type for biological source of materials seqset.asn - 1) added new set classes mut-set = set of mutations of a sequence pop-set = population set (look for frequency in BioSource) phy-set = phylogenetic study submit.asn - 1) added tool field for string defining tool that made the entry 2) added user-tag field for user supplied id for this entry 3) added comment for user comments/advice to database on this entry 4) added type to indicate new, update, revise