A0Q5A1
multicom
A0Q5A1
full_length
A0Q5A1
Results of Structure Prediction for Target Name: A0Q5A1 ( Click 
)
Domain Boundary prediction ( View )
>A0Q5A1: 1-119
| 1-60: |
M | V | I | I | L | L | A | G | C | S | S | V | E | L | K | P | I | A | N | K | V | E | I | S | R | A | A | P | A | K | D | C | K | F | V | N | T | I | T | A | T | Q | G | N | F | F | T | G | A | F | T | S | N | N | N | L | Q | E | G | A |
| 61-119: |
Y | N | K | V | R | N | E | A | A | E | M | G | G | N | Y | I | Q | L | I | S | S | Q | A | G | N | T | G | E | G | S | G | F | N | G | D | Y | N | S | S | Y | Q | Q | T | N | Y | T | V | T | G | S | V | Y | N | C | P | I | N | N | S |
| 1-60: |
C | E | E | H | E | E | H | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | E | E | E | C | C | C | C | C | C | H | H | H | H | H | H | H |
| 61-119: |
H | H | H | H | H | H | H | H | H | H | H | C | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C |
| |
| | H(Helix): 20(16.81%) | E(Strand): 34(28.57%) | C(Coil): 65(54.62%) |
| 1-60: |
E | B | B | B | B | B | B | B | B | B | E | E | E | B | E | E | E | B | E | E | B | E | B | E | E | E | E | E | E | E | E | B | E | E | E | B | E | B | E | B | E | E | B | B | B | B | B | B | B | B | B | B | E | E | E | B | B | E | B | B |
| 61-119: |
B | E | E | B | E | E | E | B | E | E | B | E | B | B | B | B | B | B | B | B | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | B | E | E | E | E | E | E | E | E | B | B | B | B | B | E | B | B | E | B | E | E | E | E | E |
| |
| | e(Exposed): 66(55.46%) | b(Buried): 53(44.54%) |
| 1-60: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T | T | T | T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T |
| |
| | N(Normal): 106(89.08%) | T(Disorder): 13(10.92%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.99 |
98.65 |
| TopL/2 |
0.98 |
101.88 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
98.32 |
| Top2L |
67.65 |
| Alignment |
Number |
| N |
2312 |
| Neff |
571 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.8833 |
| Model 3 |
0.9108 |
| Model 4 |
0.9161 |
| Model 5 |
0.8802 |
| Average |
0.89760 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3qkb |
0.61852 |
| 5zap |
0.59002 |
| 5evf |
0.58259 |
| 1vr4 |
0.57989 |
| 2y1b |
0.57582 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
100.00 |
| Top2L |
69.75 |
| Alignment |
Number |
| N |
2312 |
| Neff |
571 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8833 |
| Model 3 |
0.8760 |
| Model 4 |
0.8652 |
| Model 5 |
0.8762 |
| Average |
0.87518 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3qkb |
0.61641 |
| 5evf |
0.59631 |
| 5zap |
0.58397 |
| 2y1b |
0.58017 |
| 1vr4 |
0.57846 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
99.16 |
| Top2L |
70.59 |
| Alignment |
Number |
| N |
2312 |
| Neff |
571 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9108 |
| Model 2 |
0.8760 |
| Model 4 |
0.8701 |
| Model 5 |
0.8418 |
| Average |
0.87467 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3qkb |
0.63251 |
| 5zap |
0.59477 |
| 5evf |
0.58650 |
| 1vr4 |
0.58174 |
| 2y1b |
0.58015 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
98.32 |
| Top2L |
66.39 |
| Alignment |
Number |
| N |
2312 |
| Neff |
571 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9161 |
| Model 2 |
0.8652 |
| Model 3 |
0.8701 |
| Model 5 |
0.8747 |
| Average |
0.88152 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3qkb |
0.62102 |
| 5zap |
0.60093 |
| 1vr4 |
0.58145 |
| 5evf |
0.57872 |
| 2y1b |
0.57715 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
100.00 |
| Top2L |
70.17 |
| Alignment |
Number |
| N |
2312 |
| Neff |
571 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8802 |
| Model 2 |
0.8762 |
| Model 3 |
0.8418 |
| Model 4 |
0.8747 |
| Average |
0.86823 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3qkb |
0.61795 |
| 5evf |
0.58981 |
| 1vr4 |
0.58044 |
| 2y1b |
0.57611 |
| 2l8y |
0.57427 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
