O05888
multicom
O05888
full_length
O05888
Results of Structure Prediction for Target Name: O05888 ( Click 
)
Domain Boundary prediction ( View )
>O05888: 1-280
| 1-60: |
M | S | P | R | V | P | R | L | R | W | D | D | P | F | R | A | L | D | M | L | A | S | L | W | S | S | T | G | M | S | L | V | S | A | G | A | A | Q | A | V | A | A | P | Y | R | T | L | F | T | T | L | Q | Q | L | L | I | G | K | E | V |
| 61-119: |
T | V | R | I | G | D | H | D | V | V | L | T | V | T | E | L | D | S | A | L | E | P | Q | G | L | A | V | G | Q | L | G | E | V | R | V | A | A | R | G | I | S | W | D | Q | H | H | L | H | S | A | V | A | V | L | R | N | V | H | I | R |
| 121-179: |
P | G | V | P | P | L | V | I | A | A | P | V | E | L | S | S | A | L | P | T | E | I | F | D | D | V | L | R | Q | A | T | P | Q | L | R | G | E | L | S | E | S | G | A | A | R | L | R | W | A | R | R | P | D | W | G | G | L | E | V | D |
| 181-239: |
V | D | V | A | G | T | T | S | Q | T | T | L | W | L | R | P | R | T | V | I | T | G | Q | R | R | W | T | L | P | A | R | T | P | A | Y | R | V | P | L | P | E | L | P | H | G | L | R | I | T | D | V | S | L | A | A | D | C | L | Q | L |
| 241-280: |
S | A | L | L | P | E | W | R | T | E | L | P | L | R | Y | L | E | S | V | I | T | Q | L | S | Q | G | A | L | S | F | V | W | P | P | L | R | S | G | A | D |
| 1-60: |
C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | C | C | C | H | H | H | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | E | E |
| 61-119: |
E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | C | C | C | C | C | C | H | C | H | C | E | E | C | E | C | C | E | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | E | E | C |
| 121-179: |
C | C | C | C | C | E | E | E | E | C | C | E | E | E | E | E | E | E | C | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | E | E | C | C | C | C | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | E | E | E | E | E |
| 181-239: |
E | E | E | E | C | C | C | C | C | C | E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | E | E | E | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E |
| 241-280: |
E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | E | E | E | E | C | C | C | C | C | C | C | C | C |
| |
| | H(Helix): 54(19.29%) | E(Strand): 99(35.36%) | C(Coil): 127(45.36%) |
| 1-60: |
E | E | E | E | E | B | B | E | E | B | E | B | B | E | E | E | B | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | B | E | B | B | B | B | E | B | B | B | E | B | B | B | E | B | B | E | E | E | E | B |
| 61-119: |
B | B | E | B | E | E | E | E | B | E | B | B | B | E | E | B | B | E | E | B | E | B | B | B | B | B | B | B | B | B | E | E | B | E | B | B | B | E | E | B | E | B | E | E | B | E | B | E | E | B | B | B | B | B | E | E | B | E | B | E |
| 121-179: |
E | E | E | E | B | B | B | B | B | B | E | B | E | B | E | B | E | B | E | B | E | E | B | E | E | B | B | E | E | B | B | E | E | B | E | B | E | B | E | E | E | B | B | B | B | B | B | B | B | E | B | E | E | B | B | B | B | E | B | B |
| 181-239: |
B | E | B | E | E | E | E | E | E | B | B | B | B | B | E | B | E | B | B | B | B | E | E | B | B | B | E | B | E | E | E | B | E | E | B | E | B | E | B | B | E | B | E | E | E | B | E | B | B | B | B | E | B | E | E | E | B | B | B | B |
| 241-280: |
B | B | E | B | E | E | B | E | E | E | B | E | E | B | E | B | E | E | B | B | E | E | B | B | E | B | B | B | E | B | E | B | B | E | B | E | E | E | E | E |
| |
| | e(Exposed): 124(44.29%) | b(Buried): 156(55.71%) |
| 1-60: |
T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-239: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 241-280: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T |
| |
| | N(Normal): 271(96.79%) | T(Disorder): 9(3.21%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.94 |
93.51 |
| TopL/2 |
0.79 |
83.12 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
84.29 |
| TopL |
54.29 |
| Top2L |
29.29 |
| Alignment |
Number |
| N |
4890 |
| Neff |
637 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.7337 |
| Model 3 |
0.7424 |
| Model 4 |
0.8198 |
| Model 5 |
0.8274 |
| Average |
0.78082 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4ews |
0.51323 |
| 2obd |
0.50559 |
| 1bp1 |
0.49454 |
| 1ewf |
0.48869 |
| 4f2a |
0.47608 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
85.71 |
| TopL |
53.21 |
| Top2L |
28.21 |
| Alignment |
Number |
| N |
4890 |
| Neff |
637 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.7337 |
| Model 3 |
0.7633 |
| Model 4 |
0.7631 |
| Model 5 |
0.7435 |
| Average |
0.75090 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4f2a |
0.44826 |
| 6cmx |
0.44460 |
| 2obd |
0.44162 |
| 4ews |
0.44132 |
| 1ewf |
0.44125 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
84.29 |
| TopL |
54.64 |
| Top2L |
30.00 |
| Alignment |
Number |
| N |
4890 |
| Neff |
637 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.7424 |
| Model 2 |
0.7633 |
| Model 4 |
0.7570 |
| Model 5 |
0.7067 |
| Average |
0.74235 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4ews |
0.47026 |
| 4f2a |
0.46722 |
| 6abu |
0.44217 |
| 6ad4 |
0.44146 |
| 3am9 |
0.44071 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
85.00 |
| TopL |
53.57 |
| Top2L |
29.29 |
| Alignment |
Number |
| N |
4890 |
| Neff |
637 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8198 |
| Model 2 |
0.7631 |
| Model 3 |
0.7570 |
| Model 5 |
0.8168 |
| Average |
0.78917 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4ews |
0.48265 |
| 4f2a |
0.48070 |
| 1bp1 |
0.46083 |
| 1ewf |
0.45408 |
| 2obd |
0.45180 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
84.29 |
| TopL |
53.21 |
| Top2L |
29.29 |
| Alignment |
Number |
| N |
4890 |
| Neff |
637 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8274 |
| Model 2 |
0.7435 |
| Model 3 |
0.7067 |
| Model 4 |
0.8168 |
| Average |
0.77360 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4ews |
0.49337 |
| 1bp1 |
0.48582 |
| 1ewf |
0.47823 |
| 4xou |
0.45082 |
| 3n8g |
0.44827 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
