P01732
multicom
P01732
full_length
P01732
Results of Structure Prediction for Target Name: P01732 ( Click 
)
Domain Boundary prediction ( View )
>P01732: 1-235
| 1-60: |
M | A | L | P | V | T | A | L | L | L | P | L | A | L | L | L | H | A | A | R | P | S | Q | F | R | V | S | P | L | D | R | T | W | N | L | G | E | T | V | E | L | K | C | Q | V | L | L | S | N | P | T | S | G | C | S | W | L | F | Q | P |
| 61-119: |
R | G | A | A | A | S | P | T | F | L | L | Y | L | S | Q | N | K | P | K | A | A | E | G | L | D | T | Q | R | F | S | G | K | R | L | G | D | T | F | V | L | T | L | S | D | F | R | R | E | N | E | G | Y | Y | F | C | S | A | L | S | N |
| 121-179: |
S | I | M | Y | F | S | H | F | V | P | V | F | L | P | A | K | P | T | T | T | P | A | P | R | P | P | T | P | A | P | T | I | A | S | Q | P | L | S | L | R | P | E | A | C | R | P | A | A | G | G | A | V | H | T | R | G | L | D | F | A |
| 181-235: |
C | D | I | Y | I | W | A | P | L | A | G | T | C | G | V | L | L | L | S | L | V | I | T | L | Y | C | N | H | R | N | R | R | R | V | C | K | C | P | R | P | V | V | K | S | G | D | K | P | S | L | S | A | R | Y | V |
| 1-60: |
C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | E | E | E | E | E | E | C |
| 61-119: |
C | C | C | C | C | C | C | E | E | E | E | E | E | C | C | C | C | C | E | E | C | C | C | C | C | C | C | C | E | E | E | E | E | E | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C |
| 121-179: |
C | E | E | E | E | C | C | C | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E |
| 181-235: |
E | E | E | E | E | E | E | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
|
| | H(Helix): 35(14.89%) | E(Strand): 67(28.51%) | C(Coil): 133(56.6%) |
| 1-60: |
E | E | E | E | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | E | E | E | E | B | E | B | E | E | E | E | E | E | B | E | E | E | E | E | B | E | B | E | B | E | B | E | B | E | E | E | E | B | B | B | B | B | B | B | B | E |
| 61-119: |
E | E | E | E | B | E | B | E | B | B | B | B | B | B | E | E | E | E | E | B | B | E | E | B | E | E | E | B | B | E | B | E | E | E | E | E | B | B | B | B | B | B | E | E | B | B | E | E | B | B | B | E | B | B | B | B | B | B | B | E |
| 121-179: |
B | B | B | E | B | B | E | B | B | B | B | B | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | B | E | E | E | E | E | E | E | E | E | E | E | E | B | E | B | B |
| 181-235: |
B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | E | E | E | E | E | E | B | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E |
|
| | e(Exposed): 130(55.32%) | b(Buried): 105(44.68%) |
| 1-60: |
T | T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | N | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | N | N | N | N | N |
| 181-235: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T |
|
| | N(Normal): 180(76.6%) | T(Disorder): 55(23.4%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.94 |
93.27 |
| TopL/2 |
0.77 |
80.96 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
93.62 |
| TopL/2 |
85.59 |
| TopL |
61.70 |
| Top2L |
34.89 |
| Alignment |
Number |
| N |
4451 |
| Neff |
1177 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.4580 |
| Model 3 |
0.5097 |
| Model 4 |
0.5176 |
| Model 5 |
0.7307 |
| Average |
0.55400 |
Radius Gyration
|
|
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
95.76 |
| TopL |
67.23 |
| Top2L |
35.74 |
| Alignment |
Number |
| N |
4451 |
| Neff |
1177 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.4580 |
| Model 3 |
0.4422 |
| Model 4 |
0.4398 |
| Model 5 |
0.4500 |
| Average |
0.44750 |
Radius Gyration
|
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
84.75 |
| TopL |
57.45 |
| Top2L |
32.34 |
| Alignment |
Number |
| N |
4451 |
| Neff |
1177 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5097 |
| Model 2 |
0.4422 |
| Model 4 |
0.8744 |
| Model 5 |
0.5121 |
| Average |
0.58460 |
Radius Gyration
|
|
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.87 |
| TopL/2 |
88.98 |
| TopL |
59.57 |
| Top2L |
34.47 |
| Alignment |
Number |
| N |
4451 |
| Neff |
1177 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5176 |
| Model 2 |
0.4398 |
| Model 3 |
0.8744 |
| Model 5 |
0.5140 |
| Average |
0.58645 |
Radius Gyration
|
|
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.87 |
| TopL/2 |
86.44 |
| TopL |
60.00 |
| Top2L |
33.40 |
| Alignment |
Number |
| N |
4451 |
| Neff |
1177 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.7307 |
| Model 2 |
0.4500 |
| Model 3 |
0.5121 |
| Model 4 |
0.5140 |
| Average |
0.55170 |
Radius Gyration
|
|
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
