P44137
multicom
P44137
full_length
P44137
Results of Structure Prediction for Target Name: P44137 ( Click 
)
Domain Boundary prediction ( View )
>P44137: 1-206
| 1-60: |
M | K | T | Y | S | L | L | L | G | L | F | I | S | F | G | V | L | A | H | P | H | A | F | I | D | I | Q | T | T | P | I | I | E | N | N | Q | L | T | G | F | S | M | K | W | T | L | D | E | P | S | S | S | A | V | I | Y | D | M | K | Q |
| 61-119: |
A | R | T | K | A | E | K | Q | K | L | L | D | D | V | M | G | N | I | V | S | E | H | Y | F | S | Y | L | Y | D | A | Q | N | N | K | I | K | Y | S | P | R | P | K | N | Y | G | I | N | V | Q | G | L | Q | L | Q | Y | Y | F | D | V | P |
| 121-179: |
L | A | H | P | Q | K | L | E | K | N | T | F | S | L | Q | T | Y | D | P | T | Y | Y | V | A | M | T | Y | A | S | K | S | A | V | D | F | S | A | L | S | K | N | C | Q | G | K | L | I | E | P | N | V | D | E | K | I | Q | A | Y | A | S |
| 181-206: |
S | L | D | K | S | Q | K | N | E | D | D | S | L | G | V | M | F | A | Q | K | I | I | I | Q | C | E |
| 1-60: |
C | H | H | H | H | H | H | H | H | H | H | C | C | C | C | H | C | C | C | C | C | E | E | E | E | E | E | E | E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E | E | E | C | H | H | H | H | H | H | H | H | H | C | C | C | C |
| 61-119: |
C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | E | E | E | C | C | C | C | C | C | C | E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E |
| 121-179: |
C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | H | H | H | H | H | H | H | H |
| 181-206: |
H | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | E | E | E | E | E | C | C |
|
| | H(Helix): 52(25.24%) | E(Strand): 66(32.04%) | C(Coil): 88(42.72%) |
| 1-60: |
E | E | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | B | B | B | B | B | B | B | B | B | E | B | E | B | E | B | E | E | E | E | B | E | B | B | E | B | E | B | B | B | B | E | B | B | B | B | B | B | B | B | B | B | E | E |
| 61-119: |
E | E | E | E | E | E | B | E | E | B | B | E | E | B | B | E | B | B | E | E | B | E | B | B | B | B | B | B | B | B | E | E | E | E | B | E | B | E | E | E | B | E | E | B | E | B | E | B | E | E | E | B | B | B | B | B | B | B | B | E |
| 121-179: |
B | E | E | E | B | E | B | E | E | E | E | B | B | B | B | B | B | B | E | B | B | B | B | B | B | B | B | E | E | E | E | E | B | E | B | E | E | B | E | E | E | B | E | B | E | B | E | E | B | E | B | E | E | E | B | B | E | B | B | E |
| 181-206: |
E | B | E | E | E | E | E | E | E | E | E | E | B | B | E | B | B | B | E | E | B | E | B | E | B | E |
|
| | e(Exposed): 94(45.63%) | b(Buried): 112(54.37%) |
| 1-60: |
T | T | T | T | T | N | N | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-206: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
|
| | N(Normal): 197(95.63%) | T(Disorder): 9(4.37%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.98 |
96.93 |
| TopL/2 |
0.93 |
96.90 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
92.72 |
| Top2L |
61.89 |
| Alignment |
Number |
| N |
1434 |
| Neff |
654 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9728 |
| Model 3 |
0.9522 |
| Model 4 |
0.9587 |
| Model 5 |
0.8050 |
| Average |
0.92218 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6uwz |
0.56450 |
| 5o8f |
0.56255 |
| 5ojm |
0.56215 |
| 6i53 |
0.56196 |
| 5fjv |
0.56163 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
99.03 |
| TopL |
93.20 |
| Top2L |
62.62 |
| Alignment |
Number |
| N |
1434 |
| Neff |
654 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9728 |
| Model 3 |
0.9652 |
| Model 4 |
0.9721 |
| Model 5 |
0.8046 |
| Average |
0.92867 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5ojm |
0.56512 |
| 5o8f |
0.56512 |
| 6uwz |
0.56415 |
| 6i53 |
0.56399 |
| 6huo |
0.56272 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
92.72 |
| Top2L |
63.35 |
| Alignment |
Number |
| N |
1434 |
| Neff |
654 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9522 |
| Model 2 |
0.9652 |
| Model 4 |
0.9763 |
| Model 5 |
0.8027 |
| Average |
0.92410 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5ojm |
0.56601 |
| 5o8f |
0.56577 |
| 6i53 |
0.56452 |
| 6huo |
0.56340 |
| 4cof |
0.56322 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
100.00 |
| TopL |
93.69 |
| Top2L |
64.08 |
| Alignment |
Number |
| N |
1434 |
| Neff |
654 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9587 |
| Model 2 |
0.9721 |
| Model 3 |
0.9763 |
| Model 5 |
0.8018 |
| Average |
0.92722 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5ojm |
0.56596 |
| 6uwz |
0.56564 |
| 6i53 |
0.56497 |
| 5o8f |
0.56489 |
| 6huk |
0.56396 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.06 |
| TopL |
88.83 |
| Top2L |
53.88 |
| Alignment |
Number |
| N |
1434 |
| Neff |
654 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8050 |
| Model 2 |
0.8046 |
| Model 3 |
0.8027 |
| Model 4 |
0.8018 |
| Average |
0.80353 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5hbt |
0.55908 |
| 6d6t |
0.55776 |
| 6d6u |
0.55660 |
| 2bj0 |
0.55616 |
| 6i53 |
0.55565 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
