P44196
multicom
P44196
full_length
P44196
Results of Structure Prediction for Target Name: P44196 ( Click 
)
Domain Boundary prediction ( View )
>P44196: 1-278
| 1-60: |
M | K | K | T | L | I | T | S | L | L | V | L | S | G | I | A | Q | A | H | E | V | W | V | Q | A | P | T | K | L | A | S | G | S | V | L | K | A | E | L | A | Y | G | D | Y | P | Y | V | E | K | I | P | E | A | R | L | K | I | F | A | P |
| 61-119: |
M | E | I | I | H | Q | N | G | E | K | Q | T | L | I | Q | K | G | E | N | Y | Q | Y | Q | S | E | K | A | L | S | D | G | S | Y | W | V | T | A | T | Y | K | P | T | F | W | S | Q | N | A | E | G | W | K | M | D | N | L | K | G | L | E |
| 121-179: |
N | P | T | Y | C | E | Q | T | Q | M | F | G | K | S | L | V | T | V | G | K | K | P | L | N | A | E | M | A | M | T | R | V | G | L | P | L | E | I | V | P | L | R | D | P | S | K | A | K | S | G | E | P | F | P | V | Q | I | F | Y | Q |
| 181-239: |
D | Q | P | L | A | G | E | T | V | I | A | T | A | D | T | I | I | V | K | D | L | E | A | S | T | G | H | R | E | P | Q | G | F | S | G | K | T | D | S | Q | G | R | V | N | I | I | P | L | I | D | G | I | W | K | I | K | V | I | H | K |
| 241-278: |
T | P | F | A | D | Q | Q | I | C | Q | Q | S | A | S | Y | S | T | L | I | L | P | V | G | K | G | L | A | K | L | P | P | K | P | E | H | H | H | H |
| 1-60: |
C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | E | E | E | E | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| 61-119: |
E | E | E | E | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | C | E | E | E | E | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| 121-179: |
C | H | H | H | H | H | H | H | H | H | H | H | H | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C |
| 181-239: |
C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | E | E | E | E | E | C | C | C | C | C | E | E | E | E | E | E | E | E | E |
| 241-278: |
C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | E | E | E | C | C | H | H | C | C | C | C | C | C | C | C | C | C | C | C |
| |
| | H(Helix): 31(11.15%) | E(Strand): 91(32.73%) | C(Coil): 156(56.12%) |
| 1-60: |
E | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | E | E | E | E | E | E | E | E | B | E | B | B | B | B | B | B | B | B | E | E | E | E | E | B | E | E | E | E | B | E | E | B | E | E |
| 61-119: |
B | E | B | B | B | E | E | E | E | E | B | E | B | E | E | E | E | E | E | B | E | B | E | B | E | E | E | B | E | E | B | B | B | B | B | B | B | B | B | E | B | B | B | B | B | E | E | E | E | E | B | E | E | E | E | E | E | E | B | E |
| 121-179: |
E | B | E | B | B | E | B | B | B | E | B | B | B | B | B | B | B | B | B | E | E | E | E | E | E | E | E | B | E | E | E | B | E | B | E | B | B | B | B | B | B | E | E | B | E | E | B | E | E | E | E | E | B | E | B | B | B | B | B | E |
| 181-239: |
B | E | B | B | E | E | B | E | B | B | B | B | B | E | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | B | B | E | B | E | B | E | E | E | B | E | B | E | B | E | B | E | E | E | B | B | B | B | B | B | B | E | B | E |
| 241-278: |
E | E | B | E | E | E | E | E | B | E | E | E | B | B | B | B | B | B | B | B | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E |
| |
| | e(Exposed): 149(53.6%) | b(Buried): 129(46.4%) |
| 1-60: |
T | T | T | T | T | T | T | T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-239: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 241-278: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T | T | T | T | T | T | T | T | T |
| |
| | N(Normal): 253(91.01%) | T(Disorder): 25(8.99%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.97 |
96.67 |
| TopL/2 |
0.94 |
97.80 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
87.50 |
| TopL/2 |
90.65 |
| TopL |
80.58 |
| Top2L |
54.86 |
| Alignment |
Number |
| N |
3123 |
| Neff |
1167 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.8410 |
| Model 3 |
0.8157 |
| Model 4 |
0.8224 |
| Model 5 |
0.8572 |
| Average |
0.83407 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3amz |
0.42926 |
| 2e1q |
0.42895 |
| 2e3t |
0.42871 |
| 6abu |
0.42861 |
| 1fo4 |
0.42757 |
|
Note: This is multi-domain structure, check alignments and domain qualities in individual domains!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
87.50 |
| TopL/2 |
89.93 |
| TopL |
78.78 |
| Top2L |
53.78 |
| Alignment |
Number |
| N |
3123 |
| Neff |
1167 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8410 |
| Model 3 |
0.8591 |
| Model 4 |
0.8695 |
| Model 5 |
0.8270 |
| Average |
0.84915 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3l8q |
0.45305 |
| 5xxz |
0.41893 |
| 1dgj |
0.41609 |
| 1wyg |
0.41523 |
| 1xf1 |
0.41174 |
|
Note: This is multi-domain structure, check alignments and domain qualities in individual domains!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
85.71 |
| TopL/2 |
89.93 |
| TopL |
79.14 |
| Top2L |
54.68 |
| Alignment |
Number |
| N |
3123 |
| Neff |
1167 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8157 |
| Model 2 |
0.8591 |
| Model 4 |
0.9051 |
| Model 5 |
0.7866 |
| Average |
0.84162 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3l8q |
0.44801 |
| 6vjb |
0.44028 |
| 3una |
0.43632 |
| 3eif |
0.43428 |
| 2e1q |
0.43406 |
|
Note: This is multi-domain structure, check alignments and domain qualities in individual domains!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
89.29 |
| TopL/2 |
89.93 |
| TopL |
80.58 |
| Top2L |
54.50 |
| Alignment |
Number |
| N |
3123 |
| Neff |
1167 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8224 |
| Model 2 |
0.8695 |
| Model 3 |
0.9051 |
| Model 5 |
0.8177 |
| Average |
0.85367 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3l8q |
0.44917 |
| 6vjb |
0.42770 |
| 4ytz |
0.42018 |
| 6ad4 |
0.42010 |
| 4yrw |
0.41901 |
|
Note: This is multi-domain structure, check alignments and domain qualities in individual domains!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
87.50 |
| TopL/2 |
89.93 |
| TopL |
79.14 |
| Top2L |
53.24 |
| Alignment |
Number |
| N |
3123 |
| Neff |
1167 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8572 |
| Model 2 |
0.8270 |
| Model 3 |
0.7866 |
| Model 4 |
0.8177 |
| Average |
0.82212 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6ac4 |
0.44765 |
| 2e1q |
0.44756 |
| 2ckj |
0.44441 |
| 3l4p |
0.44116 |
| 1sij |
0.44091 |
|
Note: This is multi-domain structure, check alignments and domain qualities in individual domains!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
