P44203
multicom
P44203
full_length
P44203
Results of Structure Prediction for Target Name: P44203 ( Click 
)
Domain Boundary prediction ( View )
>P44203: 1-168
| 1-60: |
M | F | L | M | W | A | L | R | L | V | Y | V | L | V | S | N | G | Y | F | V | K | Q | L | F | A | R | A | S | I | I | G | V | A | L | L | L | S | A | C | A | T | V | P | M | A | S | V | E | E | S | N | T | A | K | Q | F | R | S | P | E |
| 61-119: |
K | G | N | S | G | L | Y | I | Y | R | D | S | F | I | G | K | A | L | K | K | D | L | Y | I | D | D | K | F | I | G | E | S | A | P | D | V | F | F | Y | K | T | I | K | A | G | E | H | K | I | S | T | E | S | E | F | S | N | S | D | L |
| 121-168: |
N | I | K | T | E | S | G | K | N | Y | F | I | R | Q | Y | T | K | F | G | V | F | V | G | G | A | N | L | E | Q | V | S | E | E | E | G | K | K | A | I | S | K | L | N | M | A | V | S | H |
| 1-60: |
C | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | C | C | C | C | C |
| 61-119: |
C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | E | E | E | E | C | C | C | E | E | E | E | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | E | E |
| 121-168: |
E | E | E | E | C | C | C | C | E | E | E | E | E | E | E | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | C | H | H | H | H | H | H | H | H | H | H | E | E | E | E | E | C | C |
| |
| | H(Helix): 52(30.95%) | E(Strand): 58(34.52%) | C(Coil): 58(34.52%) |
| 1-60: |
E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | E | B | E | E | E | E | E | E | E | B | E | E | B | E | E | E | E |
| 61-119: |
E | E | E | B | B | B | B | B | B | B | E | E | B | B | B | B | B | B | E | B | E | B | B | B | B | E | E | B | B | B | E | B | E | E | E | B | B | B | B | B | E | B | E | E | E | E | B | B | B | B | B | E | B | E | E | E | E | E | E | B |
| 121-168: |
E | B | E | B | E | E | E | E | B | B | B | B | B | B | B | B | E | B | B | B | B | B | B | E | B | E | B | E | E | B | E | E | E | E | B | E | E | E | B | E | E | B | E | B | B | E | E | E |
| |
| | e(Exposed): 68(40.48%) | b(Buried): 100(59.52%) |
| 1-60: |
T | N | T | T | N | N | T | T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-168: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T |
| |
| | N(Normal): 158(94.05%) | T(Disorder): 10(5.95%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.96 |
95.43 |
| TopL/2 |
0.84 |
88.09 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.81 |
| TopL |
74.40 |
| Top2L |
41.96 |
| Alignment |
Number |
| N |
12501 |
| Neff |
3569 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.8411 |
| Model 3 |
0.7495 |
| Model 4 |
0.8737 |
| Model 5 |
0.7225 |
| Average |
0.79670 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5a9d |
0.48205 |
| 1r6v |
0.47494 |
| 6v85 |
0.46750 |
| 1sh3 |
0.46498 |
| 6y6k |
0.46368 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.81 |
| TopL |
76.19 |
| Top2L |
42.56 |
| Alignment |
Number |
| N |
12501 |
| Neff |
3569 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8411 |
| Model 3 |
0.8642 |
| Model 4 |
0.8692 |
| Model 5 |
0.7137 |
| Average |
0.82205 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5a9d |
0.48840 |
| 7btf |
0.48087 |
| 1r6v |
0.47485 |
| 4ykn |
0.46501 |
| 6m71 |
0.46349 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.81 |
| TopL |
75.00 |
| Top2L |
43.15 |
| Alignment |
Number |
| N |
12501 |
| Neff |
3569 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.7495 |
| Model 2 |
0.8642 |
| Model 4 |
0.8241 |
| Model 5 |
0.7084 |
| Average |
0.78655 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5a9d |
0.48811 |
| 1r6v |
0.46557 |
| 4k4k |
0.46367 |
| 6y6k |
0.46088 |
| 5a9h |
0.45907 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.81 |
| TopL |
73.81 |
| Top2L |
42.26 |
| Alignment |
Number |
| N |
12501 |
| Neff |
3569 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8737 |
| Model 2 |
0.8692 |
| Model 3 |
0.8241 |
| Model 5 |
0.7140 |
| Average |
0.82025 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5a9d |
0.48271 |
| 1r6v |
0.47425 |
| 2bvm |
0.47138 |
| 6oq5 |
0.47063 |
| 2bvl |
0.47024 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.81 |
| TopL |
75.00 |
| Top2L |
41.67 |
| Alignment |
Number |
| N |
12501 |
| Neff |
3569 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.7225 |
| Model 2 |
0.7137 |
| Model 3 |
0.7084 |
| Model 4 |
0.7140 |
| Average |
0.71465 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3una |
0.51056 |
| 3amz |
0.51039 |
| 3unc |
0.51024 |
| 3bdj |
0.50977 |
| 3uni |
0.50966 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
