P44241
multicom
P44241
full_length
P44241
Results of Structure Prediction for Target Name: P44241 ( Click 
)
Domain Boundary prediction ( View )
>P44241: 1-168
| 1-60: |
M | L | A | V | R | C | D | Q | L | V | E | V | N | S | K | A | H | T | L | I | K | E | R | M | P | G | Q | A | T | L | L | L | E | E | W | E | G | F | Y | G | L | P | E | C | G | R | Q | I | V | G | K | T | L | V | Q | R | Q | K | Q | V |
| 61-119: |
Q | E | K | E | N | E | V | G | S | N | S | K | R | F | L | E | E | I | A | T | Q | A | G | F | K | V | R | V | V | N | H | Y | P | H | H | C | L | R | D | C | T | Y | P | L | Y | E | Q | A | N | H | W | R | I | F | M | Y | T | P | A | V |
| 121-168: |
S | S | I | R | Y | A | T | C | L | D | D | V | V | K | N | L | T | I | F | E | R | N | K | E | L | E | C | L | L | K | R | Y | Q | Y | A | H | L | E | F | V | F | I | Y | E | E | E | T | Q |
| 1-60: |
C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H |
| 61-119: |
H | H | H | H | H | H | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | C | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C |
| 121-168: |
C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | H | H | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C |
|
| | H(Helix): 73(43.45%) | E(Strand): 28(16.67%) | C(Coil): 67(39.88%) |
| 1-60: |
E | B | E | B | B | B | E | E | B | E | E | B | E | E | E | B | E | E | B | B | E | E | B | E | B | E | E | B | E | E | B | B | E | E | B | B | E | B | B | E | B | B | E | B | B | B | E | E | E | E | E | B | B | E | E | B | B | E | E | B |
| 61-119: |
B | E | B | B | E | E | E | E | E | B | B | B | E | B | B | B | E | B | B | E | E | B | E | B | E | B | B | B | E | E | B | B | E | B | B | B | B | B | E | B | E | B | B | B | B | E | E | E | B | B | B | B | B | B | B | B | B | E | E | E |
| 121-168: |
E | B | B | B | B | B | B | B | E | B | E | B | E | E | B | B | B | B | B | E | E | E | E | B | B | B | B | B | B | E | E | B | E | E | B | B | B | B | B | B | B | B | B | E | E | E | E | E |
|
| | e(Exposed): 73(43.45%) | b(Buried): 95(56.55%) |
| 1-60: |
T | N | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-168: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T |
|
| | N(Normal): 161(95.83%) | T(Disorder): 7(4.17%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.90 |
89.27 |
| TopL/2 |
0.74 |
77.86 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
88.10 |
| TopL |
58.33 |
| Top2L |
31.85 |
| Alignment |
Number |
| N |
2011 |
| Neff |
739 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9206 |
| Model 3 |
0.9028 |
| Model 4 |
0.6883 |
| Model 5 |
0.8512 |
| Average |
0.84072 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6n38 |
0.46618 |
| 1x0u |
0.45874 |
| 2xt6 |
0.45841 |
| 5w1h |
0.45810 |
| 5lm9 |
0.45739 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
91.67 |
| TopL |
60.12 |
| Top2L |
31.85 |
| Alignment |
Number |
| N |
2011 |
| Neff |
739 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9206 |
| Model 3 |
0.8908 |
| Model 4 |
0.7014 |
| Model 5 |
0.8414 |
| Average |
0.83855 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6n38 |
0.48073 |
| 3zuq |
0.45963 |
| 2hxg |
0.45830 |
| 2xt6 |
0.45720 |
| 2ajt |
0.45693 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
91.67 |
| TopL |
58.93 |
| Top2L |
31.25 |
| Alignment |
Number |
| N |
2011 |
| Neff |
739 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9028 |
| Model 2 |
0.8908 |
| Model 4 |
0.6949 |
| Model 5 |
0.8695 |
| Average |
0.83950 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5i6f |
0.47122 |
| 6n38 |
0.46979 |
| 2xt6 |
0.46739 |
| 3a9r |
0.46180 |
| 3a9s |
0.46110 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
94.05 |
| TopL |
58.33 |
| Top2L |
29.17 |
| Alignment |
Number |
| N |
2011 |
| Neff |
739 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.6883 |
| Model 2 |
0.7014 |
| Model 3 |
0.6949 |
| Model 5 |
0.6786 |
| Average |
0.69080 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5ja2 |
0.48761 |
| 6h1v |
0.48670 |
| 6i8a |
0.48494 |
| 3e7w |
0.48131 |
| 2p2f |
0.47999 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
90.48 |
| TopL |
60.12 |
| Top2L |
33.63 |
| Alignment |
Number |
| N |
2011 |
| Neff |
739 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8512 |
| Model 2 |
0.8414 |
| Model 3 |
0.8695 |
| Model 4 |
0.6786 |
| Average |
0.81017 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 1l2f |
0.49175 |
| 4c22 |
0.47897 |
| 6n38 |
0.47831 |
| 1hh2 |
0.47470 |
| 4r1p |
0.47259 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
