P76065
multicom
P76065
full_length
P76065
Results of Structure Prediction for Target Name: P76065 ( Click 
)
Domain Boundary prediction ( View )
>P76065: 1-285
| 1-60: |
M | L | F | V | L | I | L | S | H | R | A | A | S | Y | G | A | I | M | A | A | L | P | Y | M | Q | L | Y | I | A | D | Y | L | A | D | T | M | H | L | S | A | E | E | H | G | A | Y | L | L | L | M | F | N | Y | W | Q | T | G | K | P | I |
| 61-119: |
P | K | N | R | L | A | K | I | A | R | L | T | N | E | R | W | A | D | V | E | P | S | L | Q | E | F | F | C | D | N | G | E | E | W | V | H | L | R | I | E | E | D | L | A | S | V | R | E | K | L | T | K | K | S | A | A | G | K | A | S |
| 121-179: |
V | Q | A | R | R | S | R | K | E | A | D | V | Q | T | K | Q | E | R | N | L | T | G | V | Q | T | D | V | E | V | V | F | E | H | D | V | N | T | K | A | T | N | K | D | T | D | K | D | L | K | T | D | P | P | L | N | P | P | R | G | N |
| 181-239: |
R | G | V | K | K | F | D | P | L | D | I | T | L | P | N | W | I | S | V | S | L | W | R | E | W | V | E | F | R | Q | A | L | R | K | P | I | R | T | E | Q | G | A | N | G | A | I | R | E | L | E | K | F | R | Q | Q | G | F | S | P | E |
| 241-285: |
Q | V | I | R | H | S | I | A | N | E | Y | Q | G | L | F | A | P | K | G | V | R | P | E | T | L | L | R | Q | V | N | T | V | S | L | P | D | S | A | I | P | P | G | F | R | G |
| 1-60: |
C | H | H | H | H | E | E | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C |
| 61-119: |
C | H | H | H | H | H | H | H | H | H | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | E | E | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C |
| 121-179: |
C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| 181-239: |
C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | C | C | C | H | H | H | H | H | H | H | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | H | H |
| 241-285: |
H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| |
| | H(Helix): 125(43.86%) | E(Strand): 4(1.4%) | C(Coil): 156(54.74%) |
| 1-60: |
E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | B | B | E | B | B | B | B | B | B | B | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | E | E | E | E | B |
| 61-119: |
E | E | E | E | B | B | B | B | B | E | B | B | E | E | E | B | E | E | B | E | E | B | B | E | E | B | B | E | E | E | E | E | E | B | B | B | E | B | B | E | E | B | B | E | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E |
| 121-179: |
E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E |
| 181-239: |
E | E | E | E | E | B | E | E | E | E | B | E | B | E | E | B | B | E | E | E | B | B | B | E | B | B | E | B | B | E | E | B | E | E | E | B | E | E | E | E | E | B | E | E | B | B | E | B | B | E | E | B | B | E | E | E | B | E | B | E |
| 241-285: |
E | B | B | E | E | B | B | E | E | E | B | E | B | B | B | E | E | E | E | E | E | E | E | E | E | E | E | E | B | E | E | B | B | E | E | E | E | E | B | B | E | B | B | E | E |
| |
| | e(Exposed): 176(61.75%) | b(Buried): 109(38.25%) |
| 1-60: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T |
| 121-179: |
T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T |
| 181-239: |
T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 241-285: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T |
| |
| | N(Normal): 192(67.37%) | T(Disorder): 93(32.63%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.48 |
49.47 |
| TopL/2 |
0.32 |
35.50 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
78.95 |
| TopL/2 |
46.85 |
| TopL |
29.82 |
| Top2L |
17.89 |
| Alignment |
Number |
| N |
1133 |
| Neff |
689 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.4994 |
| Model 3 |
0.5019 |
| Model 4 |
0.4905 |
| Model 5 |
0.5092 |
| Average |
0.50025 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 1gku |
0.45124 |
| 4mt1 |
0.44177 |
| 5xc2 |
0.43051 |
| 5xan |
0.42826 |
| 2wjy |
0.42767 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
77.19 |
| TopL/2 |
46.85 |
| TopL |
30.18 |
| Top2L |
17.54 |
| Alignment |
Number |
| N |
1133 |
| Neff |
689 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.4994 |
| Model 3 |
0.4882 |
| Model 4 |
0.4649 |
| Model 5 |
0.4776 |
| Average |
0.48253 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 1bxr |
0.44858 |
| 1m6v |
0.44727 |
| 1a9x |
0.44718 |
| 1t36 |
0.44712 |
| 1kee |
0.44651 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
77.19 |
| TopL/2 |
46.15 |
| TopL |
28.42 |
| Top2L |
17.37 |
| Alignment |
Number |
| N |
1133 |
| Neff |
689 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5019 |
| Model 2 |
0.4882 |
| Model 4 |
0.4318 |
| Model 5 |
0.4518 |
| Average |
0.46842 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6npl |
0.44291 |
| 6mix |
0.44011 |
| 6vz9 |
0.44001 |
| 3ada |
0.43472 |
| 1vrq |
0.43438 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
75.44 |
| TopL/2 |
46.15 |
| TopL |
29.12 |
| Top2L |
17.19 |
| Alignment |
Number |
| N |
1133 |
| Neff |
689 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.4905 |
| Model 2 |
0.4649 |
| Model 3 |
0.4318 |
| Model 5 |
0.4919 |
| Average |
0.46977 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 1vni |
0.45198 |
| 1vng |
0.45068 |
| 4usz |
0.45027 |
| 1vne |
0.45017 |
| 1idu |
0.45014 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
77.19 |
| TopL/2 |
46.15 |
| TopL |
28.77 |
| Top2L |
17.54 |
| Alignment |
Number |
| N |
1133 |
| Neff |
689 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5092 |
| Model 2 |
0.4776 |
| Model 3 |
0.4518 |
| Model 4 |
0.4919 |
| Average |
0.48263 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 1n5x |
0.44957 |
| 2e1q |
0.44848 |
| 6pzi |
0.44479 |
| 4q73 |
0.44264 |
| 4nmb |
0.44006 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
