P76172
multicom
P76172
full_length
P76172
Results of Structure Prediction for Target Name: P76172 ( Click 
)
Domain Boundary prediction ( View )
>P76172: 1-101
| 1-60: |
M | K | L | S | T | C | C | A | A | L | L | L | A | L | A | S | P | A | V | L | A | A | P | G | S | C | E | R | I | Q | S | D | I | S | Q | R | I | I | N | N | G | V | P | E | S | S | F | T | L | S | I | V | P | N | D | Q | V | D | Q | P |
| 61-101: |
D | S | Q | V | V | G | H | C | A | N | D | T | H | K | I | L | Y | T | R | T | T | S | G | N | V | S | A | P | A | Q | S | S | Q | D | G | A | P | A | E | P | Q |
| 1-60: |
C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | H | H | H | H | C | H | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C |
| 61-101: |
C | C | E | E | E | E | E | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| |
| | H(Helix): 33(32.67%) | E(Strand): 18(17.82%) | C(Coil): 50(49.5%) |
| 1-60: |
E | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | B | B | B | E | E | B | B | E | E | B | E | E | E | B | E | E | E | B | E | E | E | E | B | E | E | E | E | B | E | B | E | B | B | E | E | E | E | B | E | E | E |
| 61-101: |
E | E | E | B | B | B | B | B | E | E | E | E | B | B | B | B | B | B | B | E | E | E | E | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E |
| |
| | e(Exposed): 60(59.41%) | b(Buried): 41(40.59%) |
| 1-60: |
T | T | T | T | T | T | T | T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-101: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T | T |
| |
| | N(Normal): 70(69.31%) | T(Disorder): 31(30.69%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.96 |
95.32 |
| TopL/2 |
0.73 |
76.61 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
95.00 |
| TopL/2 |
72.55 |
| TopL |
38.61 |
| Top2L |
20.30 |
| Alignment |
Number |
| N |
1485 |
| Neff |
109 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9213 |
| Model 3 |
0.9161 |
| Model 4 |
0.9429 |
| Model 5 |
0.8943 |
| Average |
0.91865 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3pjx |
0.58481 |
| 3pjw |
0.57371 |
| 5jj6 |
0.55939 |
| 6i7h |
0.55519 |
| 3hoa |
0.54851 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
95.00 |
| TopL/2 |
72.55 |
| TopL |
39.60 |
| Top2L |
20.30 |
| Alignment |
Number |
| N |
1485 |
| Neff |
109 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9213 |
| Model 3 |
0.9173 |
| Model 4 |
0.9320 |
| Model 5 |
0.8787 |
| Average |
0.91233 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3pjx |
0.57633 |
| 4u0u |
0.57550 |
| 3pjw |
0.57216 |
| 4u0z |
0.56330 |
| 6i7h |
0.55676 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
95.00 |
| TopL/2 |
74.51 |
| TopL |
39.60 |
| Top2L |
20.30 |
| Alignment |
Number |
| N |
1485 |
| Neff |
109 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9161 |
| Model 2 |
0.9173 |
| Model 4 |
0.9026 |
| Model 5 |
0.8938 |
| Average |
0.90745 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3pjx |
0.57822 |
| 6o22 |
0.55778 |
| 6i7h |
0.55548 |
| 3hoa |
0.55398 |
| 5x70 |
0.55261 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
95.00 |
| TopL/2 |
76.47 |
| TopL |
41.58 |
| Top2L |
21.78 |
| Alignment |
Number |
| N |
1485 |
| Neff |
109 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9429 |
| Model 2 |
0.9320 |
| Model 3 |
0.9026 |
| Model 5 |
0.9022 |
| Average |
0.91992 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3pjx |
0.58191 |
| 5x6y |
0.57711 |
| 3pjw |
0.57326 |
| 6i7h |
0.55085 |
| 3c9b |
0.55038 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
95.00 |
| TopL/2 |
74.51 |
| TopL |
38.61 |
| Top2L |
20.30 |
| Alignment |
Number |
| N |
1485 |
| Neff |
109 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8943 |
| Model 2 |
0.8787 |
| Model 3 |
0.8938 |
| Model 4 |
0.9022 |
| Average |
0.89225 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3hoa |
0.55543 |
| 5wvu |
0.54934 |
| 5x7v |
0.54334 |
| 4ka7 |
0.54317 |
| 4ka8 |
0.54214 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
