Q2FZF3
multicom
Q2FZF3
full_length
Q2FZF3
Results of Structure Prediction for Target Name: Q2FZF3 ( Click 
)
Domain Boundary prediction ( View )
>Q2FZF3: 1-185
| 1-60: |
M | K | W | S | I | T | Q | L | R | K | Y | Q | G | K | P | F | E | F | D | Q | T | V | S | F | D | N | L | K | E | S | L | D | L | I | D | L | S | P | I | T | I | Q | G | Q | L | T | I | K | S | T | E | V | V | A | D | I | H | I | T | G |
| 61-119: |
T | Y | T | M | P | C | A | R | T | L | V | P | V | K | V | P | L | D | V | T | T | T | E | V | F | D | L | E | G | Y | N | Q | Y | N | D | D | Q | D | D | V | D | E | H | Y | H | I | I | K | D | G | M | V | N | L | Q | D | I | V | E | D |
| 121-179: |
I | V | I | I | E | K | P | M | R | A | Y | S | E | Q | S | D | Q | M | L | T | V | G | N | G | W | E | V | I | D | E | D | Q | L | D | E | L | A | K | Q | Q | E | Q | D | D | S | E | S | R | Q | V | D | P | R | L | Q | K | L | Q | Q | L |
| 181-185: |
Y | D | K | E | Q |
| 1-60: |
C | C | C | E | H | H | H | H | H | H | C | C | C | C | C | E | E | E | E | E | E | E | E | C | H | H | H | H | C | C | C | C | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E | E |
| 61-119: |
E | E | E | E | E | C | C | C | C | C | C | C | C | E | C | E | E | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | C | E | E | C | C | C | H | H | H | H | H |
| 121-179: |
H | H | H | H | C | C | C | C | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | H | H | H | H | H | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H |
| 181-185: |
H | C | C | C | C |
|
| | H(Helix): 34(18.38%) | E(Strand): 64(34.59%) | C(Coil): 87(47.03%) |
| 1-60: |
E | E | B | E | B | E | E | B | E | E | E | E | E | E | E | B | E | B | E | E | E | B | E | B | E | E | B | E | E | E | E | E | B | B | E | B | E | E | B | E | B | E | B | E | B | E | B | E | E | E | B | B | B | B | B | B | E | B | E | B |
| 61-119: |
E | B | E | B | B | B | B | B | B | B | E | E | B | E | B | E | B | E | B | E | B | E | B | B | B | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | B | B | E | B | E | E | E | E | B | E | B | B | E | B | B | B | B |
| 121-179: |
B | B | B | B | B | B | B | B | E | B | B | B | E | E | E | B | E | E | B | E | E | E | E | E | B | E | B | B | E | E | E | E | B | E | E | E | E | E | E | E | E | E | B | E | E | E | E | E | E | B | B | E | E | B | E | E | B | E | E | B |
| 181-185: |
B | E | E | E | E |
|
| | e(Exposed): 110(59.46%) | b(Buried): 75(40.54%) |
| 1-60: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | N | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-185: |
N | N | T | T | T |
|
| | N(Normal): 176(95.14%) | T(Disorder): 9(4.86%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.96 |
95.00 |
| TopL/2 |
0.87 |
90.64 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.30 |
| TopL/2 |
96.77 |
| TopL |
76.76 |
| Top2L |
43.51 |
| Alignment |
Number |
| N |
6855 |
| Neff |
3057 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9562 |
| Model 3 |
0.9448 |
| Model 4 |
0.9233 |
| Model 5 |
0.9313 |
| Average |
0.93890 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3kvn |
0.49956 |
| 6t1w |
0.49829 |
| 5or1 |
0.49708 |
| 5d0o |
0.49617 |
| 5ayw |
0.49375 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.30 |
| TopL/2 |
95.70 |
| TopL |
76.22 |
| Top2L |
43.51 |
| Alignment |
Number |
| N |
6855 |
| Neff |
3057 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9562 |
| Model 3 |
0.9613 |
| Model 4 |
0.9534 |
| Model 5 |
0.9327 |
| Average |
0.95090 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6t1w |
0.50363 |
| 5d0o |
0.50169 |
| 5ayw |
0.49980 |
| 3kvn |
0.49565 |
| 4k3c |
0.49465 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.30 |
| TopL/2 |
96.77 |
| TopL |
76.22 |
| Top2L |
44.05 |
| Alignment |
Number |
| N |
6855 |
| Neff |
3057 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9448 |
| Model 2 |
0.9613 |
| Model 4 |
0.9386 |
| Model 5 |
0.9387 |
| Average |
0.94585 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5or1 |
0.50328 |
| 5d0o |
0.49773 |
| 3kvn |
0.49690 |
| 6t1w |
0.49540 |
| 5ayw |
0.49507 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.30 |
| TopL/2 |
96.77 |
| TopL |
74.59 |
| Top2L |
43.78 |
| Alignment |
Number |
| N |
6855 |
| Neff |
3057 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9233 |
| Model 2 |
0.9534 |
| Model 3 |
0.9386 |
| Model 5 |
0.9280 |
| Average |
0.93583 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3kvn |
0.50948 |
| 5d0o |
0.49216 |
| 6t1w |
0.49122 |
| 4k3c |
0.49013 |
| 3slj |
0.48504 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.30 |
| TopL/2 |
96.77 |
| TopL |
77.30 |
| Top2L |
44.05 |
| Alignment |
Number |
| N |
6855 |
| Neff |
3057 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9313 |
| Model 2 |
0.9327 |
| Model 3 |
0.9387 |
| Model 4 |
0.9280 |
| Average |
0.93267 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3kvn |
0.49725 |
| 6t1w |
0.49275 |
| 5d0o |
0.49230 |
| 5ayw |
0.49020 |
| 4k3c |
0.48676 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
