Q46953
multicom
Q46953
full_length
Q46953
Results of Structure Prediction for Target Name: Q46953 ( Click 
)
Domain Boundary prediction ( View )
>Q46953: 1-109
| 1-60: |
M | N | T | L | P | A | T | I | S | Q | A | A | K | P | C | L | S | P | V | A | V | W | Q | M | L | L | T | R | L | L | E | Q | H | Y | G | L | T | L | N | D | T | P | F | S | D | E | T | V | I | K | E | H | I | D | A | G | I | T | L | A |
| 61-109: |
D | A | V | N | F | L | V | E | K | Y | E | L | V | R | I | D | H | R | G | F | S | W | Q | Q | Q | S | P | Y | I | S | V | V | D | I | L | R | A | R | R | S | T | G | L | L | K | T | N | V | K |
| 1-60: |
C | C | C | C | C | C | C | H | H | H | H | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | E | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | C | C | C | C | H | H |
| 61-109: |
H | H | H | H | H | H | H | H | H | H | H | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | C | C |
| |
| | H(Helix): 52(47.71%) | E(Strand): 4(3.67%) | C(Coil): 53(48.62%) |
| 1-60: |
E | E | E | B | E | E | E | E | E | E | B | B | E | E | B | E | B | B | B | E | B | B | B | B | B | B | B | E | B | B | E | E | B | B | B | B | B | B | E | E | B | E | B | B | E | E | E | B | B | E | E | B | B | E | E | E | B | E | B | B |
| 61-109: |
E | B | B | B | E | B | B | E | E | B | E | B | E | B | B | E | E | E | E | E | E | B | B | E | E | B | E | B | B | B | B | B | B | B | B | B | B | B | E | B | E | E | B | E | E | E | E | E | E |
| |
| | e(Exposed): 52(47.71%) | b(Buried): 57(52.29%) |
| 1-60: |
T | T | T | T | T | T | T | T | T | T | T | T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-109: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | T | T | T | T | T |
| |
| | N(Normal): 91(83.49%) | T(Disorder): 18(16.51%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.50 |
51.14 |
| TopL/2 |
0.39 |
41.94 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
86.36 |
| TopL/2 |
65.45 |
| TopL |
39.45 |
| Top2L |
22.48 |
| Alignment |
Number |
| N |
1104 |
| Neff |
57 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9437 |
| Model 3 |
0.9123 |
| Model 4 |
0.9292 |
| Model 5 |
0.9269 |
| Average |
0.92802 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4oyf |
0.56401 |
| 3fqd |
0.56290 |
| 6xwo |
0.56142 |
| 6xwp |
0.56120 |
| 6xwr |
0.56055 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
86.36 |
| TopL/2 |
63.64 |
| TopL |
38.53 |
| Top2L |
22.02 |
| Alignment |
Number |
| N |
1104 |
| Neff |
57 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9437 |
| Model 3 |
0.9167 |
| Model 4 |
0.9161 |
| Model 5 |
0.9245 |
| Average |
0.92525 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6xwr |
0.56421 |
| 6xwp |
0.56421 |
| 6xwo |
0.56371 |
| 6rvy |
0.56183 |
| 4oye |
0.56067 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
90.91 |
| TopL/2 |
67.27 |
| TopL |
42.20 |
| Top2L |
24.31 |
| Alignment |
Number |
| N |
1104 |
| Neff |
57 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9123 |
| Model 2 |
0.9167 |
| Model 4 |
0.9012 |
| Model 5 |
0.9057 |
| Average |
0.90897 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3fqd |
0.57585 |
| 4oyf |
0.56638 |
| 1r2j |
0.56609 |
| 2y35 |
0.56590 |
| 4p1a |
0.56150 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
90.91 |
| TopL/2 |
65.45 |
| TopL |
40.37 |
| Top2L |
23.39 |
| Alignment |
Number |
| N |
1104 |
| Neff |
57 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9292 |
| Model 2 |
0.9161 |
| Model 3 |
0.9012 |
| Model 5 |
0.9442 |
| Average |
0.92268 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3owa |
0.56286 |
| 4l1f |
0.55833 |
| 6rvy |
0.55795 |
| 4oye |
0.55770 |
| 4oyf |
0.55749 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
86.36 |
| TopL/2 |
67.27 |
| TopL |
42.20 |
| Top2L |
24.31 |
| Alignment |
Number |
| N |
1104 |
| Neff |
57 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9269 |
| Model 2 |
0.9245 |
| Model 3 |
0.9057 |
| Model 4 |
0.9442 |
| Average |
0.92532 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4oyf |
0.56443 |
| 2vig |
0.56145 |
| 6xwo |
0.56091 |
| 6xwr |
0.56084 |
| 6xwp |
0.56058 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
