Q57273
multicom
Q57273
full_length
Q57273
Results of Structure Prediction for Target Name: Q57273 ( Click 
)
Domain Boundary prediction ( View )
>Q57273: 1-292
| 1-60: |
M | A | I | Q | M | T | T | K | T | T | Y | Q | W | P | Q | S | K | D | I | Y | P | Y | R | P | G | R | F | D | A | P | K | H | W | R | Y | N | L | R | S | F | L | N | R | G | S | I | R | R | F | E | Q | F | I | N | Q | H | P | F | L | I |
| 61-119: |
D | I | F | N | T | H | L | D | Y | S | Y | P | V | A | C | R | F | L | D | K | R | F | N | A | S | Q | R | F | H | A | V | C | E | N | L | L | F | L | P | E | K | L | T | A | L | S | T | P | L | W | E | K | P | L | S | F | G | E | V | I |
| 121-179: |
P | D | F | E | M | T | L | S | M | T | T | H | Q | P | M | E | G | Y | W | V | L | E | L | W | H | K | P | R | N | E | L | V | Y | L | L | T | F | A | K | L | G | D | A | L | L | I | A | V | V | Q | G | P | N | F | E | G | S | K | E | M |
| 181-239: |
V | K | Q | L | T | K | L | C | H | G | L | R | P | A | Y | L | M | V | E | T | M | K | S | L | T | K | I | L | G | Y | N | K | L | L | G | I | P | Q | K | Y | Q | N | K | S | R | F | I | Q | S | K | Q | Y | T | V | D | Y | D | A | I | F |
| 241-292: |
G | E | S | G | G | E | L | K | D | Y | W | E | L | P | L | E | M | D | R | N | L | D | D | I | P | S | K | K | R | S | M | Y | R | K | R | Y | A | M | L | D | D | L | A | K | V | I | E | E | K | L | G | L |
| 1-60: |
C | C | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | E | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | H | H | H | H | H | H | H | H | H | H | H | H | C | C | H | H | H | H |
| 61-119: |
H | H | H | H | H | C | C | C | H | H | H | H | C | C | H | H | H | H | H | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | H | C | C | C | C |
| 121-179: |
C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | C | C | H | H | H | H |
| 181-239: |
H | H | H | H | H | H | H | H | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | E | E | E | E | E | C | C | C | C | C | E | H | H | H | H | C | C | C | C | E | E | E | E | C | H | H | H | H | H |
| 241-292: |
H | H | C | C | C | C | C | C | C | C | E | E | E | C | C | C | C | C | C | C | H | H | H | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C |
|
| | H(Helix): 141(48.29%) | E(Strand): 46(15.75%) | C(Coil): 105(35.96%) |
| 1-60: |
E | E | B | B | B | E | E | E | E | E | B | E | B | E | E | B | E | E | B | B | E | E | E | E | E | E | E | E | B | B | E | B | B | B | B | B | B | B | B | B | B | B | B | E | B | B | E | E | B | B | E | B | B | E | E | B | E | E | B | E |
| 61-119: |
E | B | B | E | E | B | E | E | B | B | E | E | B | B | B | B | B | B | B | E | E | B | E | B | E | E | B | B | E | B | B | B | E | B | B | E | B | B | B | E | B | B | E | E | B | B | B | B | B | B | E | E | E | B | E | B | B | E | B | E |
| 121-179: |
E | E | B | B | B | B | B | B | B | B | E | E | B | E | E | B | B | B | B | B | B | B | B | B | B | E | E | E | E | B | B | B | B | B | B | B | B | B | B | B | E | E | B | B | B | B | B | B | B | B | B | B | E | E | E | E | B | E | E | B |
| 181-239: |
B | E | E | B | B | E | E | B | E | E | B | B | B | E | B | B | B | B | B | B | B | B | B | B | B | E | B | B | E | B | E | B | B | B | B | B | B | E | E | B | B | B | B | B | B | B | E | E | E | E | E | B | E | B | B | B | E | E | B | B |
| 241-292: |
E | E | B | E | B | E | E | E | E | B | B | E | B | E | B | E | B | E | E | E | B | E | E | B | E | E | E | E | B | E | E | B | E | E | B | B | E | B | B | E | E | B | E | E | E | B | E | E | E | B | E | E |
|
| | e(Exposed): 126(43.15%) | b(Buried): 166(56.85%) |
| 1-60: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-239: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 241-292: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
|
| | N(Normal): 292(100%) | T(Disorder): 0(0%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.89 |
88.88 |
| TopL/2 |
0.73 |
76.40 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
98.28 |
| TopL/2 |
89.73 |
| TopL |
54.79 |
| Top2L |
29.79 |
| Alignment |
Number |
| N |
2952 |
| Neff |
551 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.8051 |
| Model 3 |
0.8005 |
| Model 4 |
0.9517 |
| Model 5 |
0.8057 |
| Average |
0.84075 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2eud |
0.45945 |
| 2cvx |
0.45823 |
| 2cvu |
0.45819 |
| 2cvv |
0.45817 |
| 2wgh |
0.45688 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
95.21 |
| TopL |
69.18 |
| Top2L |
41.78 |
| Alignment |
Number |
| N |
2952 |
| Neff |
551 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8051 |
| Model 3 |
0.9724 |
| Model 4 |
0.8226 |
| Model 5 |
0.9706 |
| Average |
0.89268 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3s8b |
0.46238 |
| 3rsr |
0.45488 |
| 2cvv |
0.45404 |
| 5l44 |
0.45361 |
| 5l43 |
0.45294 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
93.15 |
| TopL |
67.47 |
| Top2L |
41.10 |
| Alignment |
Number |
| N |
2952 |
| Neff |
551 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8005 |
| Model 2 |
0.9724 |
| Model 4 |
0.8197 |
| Model 5 |
0.9755 |
| Average |
0.89203 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2eud |
0.46878 |
| 3hnd |
0.46636 |
| 3k8t |
0.46514 |
| 3s8b |
0.46455 |
| 2cvv |
0.46441 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
90.41 |
| TopL |
55.48 |
| Top2L |
29.79 |
| Alignment |
Number |
| N |
2952 |
| Neff |
551 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9517 |
| Model 2 |
0.8226 |
| Model 3 |
0.8197 |
| Model 5 |
0.8238 |
| Average |
0.85445 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2zlf |
0.45594 |
| 1zyz |
0.45472 |
| 2cvx |
0.45455 |
| 3s8c |
0.45406 |
| 3s87 |
0.45399 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
93.15 |
| TopL |
66.10 |
| Top2L |
39.73 |
| Alignment |
Number |
| N |
2952 |
| Neff |
551 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.8057 |
| Model 2 |
0.9706 |
| Model 3 |
0.9755 |
| Model 4 |
0.8238 |
| Average |
0.89390 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5d1y |
0.46366 |
| 2cvu |
0.46346 |
| 3k8t |
0.46289 |
| 2eud |
0.46219 |
| 3s8b |
0.46131 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
