Q8A4K4
multicom
Q8A4K4
full_length
Q8A4K4
Results of Structure Prediction for Target Name: Q8A4K4 ( Click 
)
Domain Boundary prediction ( View )
>Q8A4K4: 1-309
| 1-60: |
M | Q | S | D | M | K | K | I | L | M | M | F | F | A | L | M | T | G | V | T | A | A | S | A | Q | L | S | S | G | D | F | F | E | G | L | S | R | K | I | G | F | S | R | M | I | A | P | H | G | L | E | I | T | Y | D | K | T | V | H | V |
| 61-119: |
I | F | P | S | P | I | K | Y | V | D | L | G | S | T | N | L | I | A | G | K | A | D | A | A | E | N | V | I | R | V | K | A | A | K | K | H | F | R | D | E | T | N | M | S | V | I | T | E | D | G | N | F | Y | T | F | N | V | R | Y | A |
| 121-179: |
D | E | P | L | L | L | N | V | E | M | C | D | F | I | H | D | G | E | T | V | N | R | P | N | N | A | M | E | I | Y | L | Q | E | L | G | N | E | S | P | R | L | V | R | L | I | M | K | S | V | H | R | Q | D | K | R | R | V | R | H | I |
| 181-239: |
G | C | K | R | F | G | V | Q | F | L | L | R | G | L | Y | T | H | N | D | L | L | Y | F | H | T | Q | L | R | N | E | T | N | V | P | F | D | V | D | F | V | T | F | K | I | V | D | K | K | I | V | K | R | T | A | M | Q | E | Q | V | I |
| 241-299: |
Y | P | L | R | A | C | N | Y | V | T | R | V | D | G | K | A | S | E | R | T | V | F | A | L | P | K | F | T | I | P | E | D | K | K | L | V | V | E | M | Y | E | K | Q | G | G | R | H | Q | M | F | E | V | D | N | E | S | L | V | R | A |
| 301-309: |
E | P | V | N | E | L | K | V | R |
| 1-60: |
C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | H | H | H | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | E | E | E | E | E |
| 61-119: |
E | E | C | C | C | E | E | E | E | E | C | C | C | C | C | E | E | E | E | C | C | C | C | C | C | C | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E | C |
| 121-179: |
C | C | C | C | C | C | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | H | H | C | C |
| 181-239: |
C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | E | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | E | E | E | E | E |
| 241-299: |
C | C | E | E | E | C | C | C | C | C | E | E | C | C | C | C | C | E | E | E | E | E | E | E | C | E | E | E | C | C | C | C | C | E | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | E | E | E | C | C | H | H | H | H | C | C |
| 301-309: |
C | C | C | C | C | E | E | C | C |
| |
| | H(Helix): 48(15.53%) | E(Strand): 107(34.63%) | C(Coil): 154(49.84%) |
| 1-60: |
E | E | E | E | B | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | E | E | E | E | E | B | E | E | E | E | E | E | E | B | E | E | E | E | E | E | E | E | E | E | B | E | B | B | E | E | E | B | B | B | B |
| 61-119: |
B | B | E | E | E | B | E | B | B | B | B | B | B | E | E | B | B | B | E | E | E | E | E | B | E | B | B | B | B | B | E | B | E | E | E | E | B | E | E | E | B | B | B | B | B | B | B | E | E | B | E | B | B | B | B | B | B | B | B | E |
| 121-179: |
E | E | B | E | E | B | E | B | E | B | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | B | E | B | E | E | B | E | E | E | B | E | E | B | B | E | B | B | B | E | E | B | E | E | E | E | E | E | E | B | E | E | B |
| 181-239: |
E | E | E | E | E | E | B | B | B | B | B | E | B | B | B | B | E | E | E | B | B | B | B | B | B | B | B | E | B | E | B | E | B | E | B | E | B | E | B | B | E | B | B | B | E | E | E | E | E | E | E | E | E | B | B | B | E | E | E | B |
| 241-299: |
E | E | B | B | E | B | E | E | B | E | E | B | E | E | E | E | E | B | B | B | B | B | B | B | E | E | B | B | B | E | E | E | E | E | B | B | B | B | B | B | E | E | E | E | E | B | E | B | E | B | E | B | E | E | E | E | B | E | E | B |
| 301-309: |
E | E | B | E | E | B | E | E | E |
| |
| | e(Exposed): 171(55.34%) | b(Buried): 138(44.66%) |
| 1-60: |
T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-239: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 241-299: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 301-309: |
N | N | N | N | T | T | T | T | T |
| |
| | N(Normal): 303(98.06%) | T(Disorder): 6(1.94%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.96 |
95.15 |
| TopL/2 |
0.86 |
90.37 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
99.35 |
| TopL |
79.94 |
| Top2L |
46.44 |
| Alignment |
Number |
| N |
2631 |
| Neff |
601 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.5544 |
| Model 3 |
0.5685 |
| Model 4 |
0.5502 |
| Model 5 |
0.5643 |
| Average |
0.55935 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6nff |
0.42227 |
| 1pj7 |
0.42046 |
| 3hhs |
0.41888 |
| 3gsi |
0.41871 |
| 1pj5 |
0.41801 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
99.35 |
| TopL |
78.64 |
| Top2L |
46.60 |
| Alignment |
Number |
| N |
2631 |
| Neff |
601 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5544 |
| Model 3 |
0.5476 |
| Model 4 |
0.5351 |
| Model 5 |
0.7251 |
| Average |
0.59055 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 5xh9 |
0.41944 |
| 3lih |
0.41925 |
| 3lfi |
0.41902 |
| 5xh8 |
0.41867 |
| 5fkb |
0.41798 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
99.35 |
| TopL |
79.61 |
| Top2L |
46.93 |
| Alignment |
Number |
| N |
2631 |
| Neff |
601 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5685 |
| Model 2 |
0.5476 |
| Model 4 |
0.5653 |
| Model 5 |
0.5486 |
| Average |
0.55750 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 4yzw |
0.44630 |
| 3hhs |
0.44472 |
| 1hc1 |
0.43924 |
| 1hcy |
0.43922 |
| 3wjm |
0.43874 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.71 |
| TopL |
77.99 |
| Top2L |
47.09 |
| Alignment |
Number |
| N |
2631 |
| Neff |
601 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5502 |
| Model 2 |
0.5351 |
| Model 3 |
0.5653 |
| Model 5 |
0.5319 |
| Average |
0.54563 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 6h3j |
0.44287 |
| 6sue |
0.44129 |
| 6suf |
0.43919 |
| 3p2d |
0.41343 |
| 1cf1 |
0.41277 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
100.00 |
| TopL/2 |
98.71 |
| TopL |
78.64 |
| Top2L |
45.63 |
| Alignment |
Number |
| N |
2631 |
| Neff |
601 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.5643 |
| Model 2 |
0.7251 |
| Model 3 |
0.5486 |
| Model 4 |
0.5319 |
| Average |
0.59248 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 3ogs |
0.42804 |
| 3ogv |
0.42795 |
| 5fmb |
0.42712 |
| 5ann |
0.42680 |
| 5fk7 |
0.42600 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
