Q8A8V1
multicom
Q8A8V1
full_length
Q8A8V1
Results of Structure Prediction for Target Name: Q8A8V1 ( Click 
)
Domain Boundary prediction ( View )
>Q8A8V1: 1-189
| 1-60: |
M | K | K | V | S | I | L | I | V | L | V | L | G | C | F | I | E | S | K | A | Q | K | V | A | L | K | S | N | L | L | Y | D | A | T | T | T | M | N | L | G | L | E | F | G | L | A | R | K | W | T | L | D | V | P | V | N | Y | N | P | W |
| 61-119: |
K | P | D | N | G | R | R | L | R | H | W | G | I | Q | P | E | V | R | Y | W | F | C | E | K | F | R | R | T | F | I | G | V | H | G | H | Y | A | D | F | N | V | G | G | F | P | D | W | S | F | I | S | E | N | M | Q | N | S | R | Y | Q |
| 121-179: |
G | Y | L | Y | G | G | G | V | S | V | G | H | S | W | I | L | K | K | R | W | S | I | E | A | S | V | G | V | G | Y | A | H | I | V | Y | D | K | Y | P | C | R | A | C | G | T | K | L | K | D | S | S | K | N | Y | F | G | P | T | K | A |
| 181-189: |
S | V | S | L | I | Y | V | I | K |
| 1-60: |
C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | E | E | E | E | E | E | C | C | E | E | E | E | E | E | E | E | E | E | C | C | C |
| 61-119: |
C | C | C | C | C | C | E | E | E | E | E | E | E | C | C | E | E | E | E | E | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C | C |
| 121-179: |
C | C | E | E | E | C | E | E | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | E | E | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | C | C | C | C | C | E | E | C | C | C | C | C | E | E | E | C | C | C | C | C |
| 181-189: |
E | E | E | E | E | E | E | E | C |
| |
| | H(Helix): 32(16.93%) | E(Strand): 82(43.39%) | C(Coil): 75(39.68%) |
| 1-60: |
E | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | B | B | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | B | E | E | B | B | B | E | B | E | B | B | B | B | B | B |
| 61-119: |
E | B | E | E | E | E | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | E | B | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | B | B | B | B | B | B | E | E | B | E | E | E | B | B | E |
| 121-179: |
B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | B | B | B | B | B | B | B | B | B | B | B | B | B | B | E | B | E | E | B | E | B | E | E | B | E | E | E | E | E | E | E | E | E | B | B | B | B | B | B | E | B |
| 181-189: |
B | B | B | B | B | B | B | B | E |
| |
| | e(Exposed): 46(24.34%) | b(Buried): 143(75.66%) |
| 1-60: |
T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-189: |
N | N | N | N | N | N | N | N | N |
| |
| | N(Normal): 188(99.47%) | T(Disorder): 1(0.53%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.94 |
93.62 |
| TopL/2 |
0.87 |
90.99 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
92.11 |
| TopL/2 |
93.68 |
| TopL |
78.84 |
| Top2L |
46.30 |
| Alignment |
Number |
| N |
15683 |
| Neff |
6305 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9015 |
| Model 3 |
0.9394 |
| Model 4 |
0.9660 |
| Model 5 |
0.9158 |
| Average |
0.93067 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2f1v |
0.70333 |
| 2x27 |
0.70327 |
| 2f1t |
0.70233 |
| 3dzm |
0.69394 |
| 1i78 |
0.66305 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
92.11 |
| TopL/2 |
91.58 |
| TopL |
76.19 |
| Top2L |
45.77 |
| Alignment |
Number |
| N |
15683 |
| Neff |
6305 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9015 |
| Model 3 |
0.8923 |
| Model 4 |
0.9230 |
| Model 5 |
0.9434 |
| Average |
0.91505 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2f1t |
0.71202 |
| 2f1v |
0.71201 |
| 2x27 |
0.71047 |
| 3dzm |
0.70666 |
| 1k24 |
0.67095 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
92.11 |
| TopL/2 |
92.63 |
| TopL |
75.66 |
| Top2L |
44.97 |
| Alignment |
Number |
| N |
15683 |
| Neff |
6305 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9394 |
| Model 2 |
0.8923 |
| Model 4 |
0.9289 |
| Model 5 |
0.9111 |
| Average |
0.91793 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2f1v |
0.69780 |
| 2f1t |
0.69681 |
| 3dzm |
0.69501 |
| 2x27 |
0.69386 |
| 1i78 |
0.66060 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
92.11 |
| TopL/2 |
93.68 |
| TopL |
74.60 |
| Top2L |
46.03 |
| Alignment |
Number |
| N |
15683 |
| Neff |
6305 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9660 |
| Model 2 |
0.9230 |
| Model 3 |
0.9289 |
| Model 5 |
0.9303 |
| Average |
0.93705 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2f1v |
0.70328 |
| 2f1t |
0.70260 |
| 2x27 |
0.70163 |
| 3dzm |
0.69029 |
| 1i78 |
0.65967 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
92.11 |
| TopL/2 |
93.68 |
| TopL |
76.72 |
| Top2L |
44.97 |
| Alignment |
Number |
| N |
15683 |
| Neff |
6305 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9158 |
| Model 2 |
0.9434 |
| Model 3 |
0.9111 |
| Model 4 |
0.9303 |
| Average |
0.92515 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2f1v |
0.70286 |
| 2x27 |
0.70155 |
| 2f1t |
0.70141 |
| 3dzm |
0.69793 |
| 1i78 |
0.66748 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
