UPI0000165324
multicom
UPI0000165324
full_length
UPI0000165324
Results of Structure Prediction for Target Name: UPI0000165324 ( Click 
)
Domain Boundary prediction ( View )
>UPI0000165324: 1-199
| 1-60: |
M | T | E | C | F | L | S | D | Q | E | I | R | K | L | N | R | D | L | R | I | L | I | A | A | N | G | T | L | T | R | V | L | N | I | V | A | D | D | E | V | I | V | Q | I | V | K | Q | R | I | H | D | V | S | P | K | L | S | E | F | E |
| 61-119: |
Q | L | G | Q | V | G | V | G | R | V | L | Q | R | Y | I | I | L | K | G | R | N | S | E | H | L | F | V | A | A | E | S | L | I | A | I | D | R | L | P | A | A | I | I | T | R | L | T | Q | T | N | D | P | L | G | E | V | M | A | A | S |
| 121-179: |
H | I | E | T | F | K | E | E | A | K | V | W | V | G | D | L | P | G | W | L | A | L | H | G | Y | Q | N | S | R | K | R | A | V | A | R | R | Y | R | V | I | S | G | G | Q | P | I | M | V | V | T | E | H | F | L | R | S | V | F | R | D |
| 181-199: |
A | P | H | E | E | P | D | R | W | Q | F | S | N | A | I | T | L | A | R |
| 1-60: |
C | C | C | C | C | C | C | H | H | C | H | H | H | C | C | H | H | H | E | E | E | E | E | C | C | C | C | H | H | H | H | H | H | H | H | H | C | C | C | E | E | E | E | E | H | H | H | H | C | C | C | C | C | C | C | C | H | H | H | H |
| 61-119: |
H | C | C | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C | C | C | C | C | C | E | E | E | E | E | E | E | E | E | C | H | H | H | C | C | H | H | H | H | H | H | H | H | H | C | C | C | C | H | H | H | H | H | H | H | H |
| 121-179: |
C | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | H | H | H | H | H | H | H | C | C | C | C | C | C | C | H | E | E | E | E | E | E | E | E | E | E | C | C | C | C | E | E | E | E | E | E | C | C | C | H | H | H | H | C | C |
| 181-199: |
C | C | C | C | C | C | C | C | C | C | C | C | C | H | H | H | H | C | C |
| |
| | H(Helix): 72(36.18%) | E(Strand): 44(22.11%) | C(Coil): 83(41.71%) |
| 1-60: |
E | E | E | E | E | B | E | E | E | E | B | E | E | B | E | E | B | B | B | B | B | B | B | B | E | B | E | B | B | E | B | B | B | B | B | B | E | E | E | B | E | B | E | E | B | E | E | E | B | E | E | E | E | E | E | E | E | E | B | E |
| 61-119: |
E | B | E | E | E | E | E | E | E | B | B | B | B | B | B | B | B | E | E | E | E | E | E | E | B | B | B | B | B | B | B | B | B | B | B | E | E | B | E | E | E | B | B | E | E | B | E | E | E | E | B | B | B | B | E | B | B | E | E | B |
| 121-179: |
E | B | E | B | B | E | E | B | B | E | B | B | E | E | E | E | E | E | E | B | B | E | E | B | E | B | E | E | E | E | E | B | B | B | B | B | B | B | B | B | B | E | E | E | B | B | B | B | B | B | B | E | B | B | E | E | B | B | E | E |
| 181-199: |
B | E | E | E | E | B | E | E | B | B | B | E | B | E | B | B | B | E | E |
| |
| | e(Exposed): 102(51.26%) | b(Buried): 97(48.74%) |
| 1-60: |
T | T | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 61-119: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 121-179: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| 181-199: |
N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N | N |
| |
| | N(Normal): 197(98.99%) | T(Disorder): 2(1.01%) |
Predicted contact map and distance map
|
Predicted distance map
|
|
Predicted contact map
|
Probability to Precision
| Long-Range |
Average probability |
Predicted precision |
| TopL/5 |
0.98 |
97.21 |
| TopL/2 |
0.91 |
94.93 |
Note: The linear model (Average probability vs Predicted precision) was trained on CASP14 dataset
|
Predicted Top 1 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.50 |
| TopL/2 |
96.00 |
| TopL |
77.39 |
| Top2L |
43.97 |
| Alignment |
Number |
| N |
3508 |
| Neff |
1019 |
|
Model comparsion
| Model |
TM-score |
| Model 2 |
0.9552 |
| Model 3 |
0.9755 |
| Model 4 |
0.9419 |
| Model 5 |
0.9565 |
| Average |
0.95728 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2nwi |
0.70964 |
| 4zsi |
0.65981 |
| 4zsk |
0.65951 |
| 3f8l |
0.65507 |
| 2ahc |
0.65153 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 2 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.50 |
| TopL/2 |
96.00 |
| TopL |
73.87 |
| Top2L |
43.22 |
| Alignment |
Number |
| N |
3508 |
| Neff |
1019 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9552 |
| Model 3 |
0.9557 |
| Model 4 |
0.9557 |
| Model 5 |
0.9580 |
| Average |
0.95615 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2nwi |
0.71175 |
| 4zsk |
0.65745 |
| 4zsi |
0.65692 |
| 3f8l |
0.65248 |
| 1g81 |
0.64707 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 3 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.50 |
| TopL/2 |
95.00 |
| TopL |
74.37 |
| Top2L |
42.96 |
| Alignment |
Number |
| N |
3508 |
| Neff |
1019 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9755 |
| Model 2 |
0.9557 |
| Model 4 |
0.9442 |
| Model 5 |
0.9550 |
| Average |
0.95760 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2nwi |
0.71054 |
| 4zsi |
0.65486 |
| 4zsk |
0.65452 |
| 2ahc |
0.65294 |
| 3f8l |
0.64886 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 4 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.50 |
| TopL/2 |
93.00 |
| TopL |
72.36 |
| Top2L |
41.46 |
| Alignment |
Number |
| N |
3508 |
| Neff |
1019 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9419 |
| Model 2 |
0.9557 |
| Model 3 |
0.9442 |
| Model 5 |
0.9379 |
| Average |
0.94493 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2nwi |
0.71220 |
| 4zsi |
0.65382 |
| 4zsk |
0.65363 |
| 3f8l |
0.64931 |
| 2ahc |
0.64504 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
Predicted Top 5 Tertiary structure
|
|
|
| Long-Range |
Precision |
| TopL/5 |
97.50 |
| TopL/2 |
94.00 |
| TopL |
74.87 |
| Top2L |
43.97 |
| Alignment |
Number |
| N |
3508 |
| Neff |
1019 |
|
Model comparsion
| Model |
TM-score |
| Model 1 |
0.9565 |
| Model 2 |
0.9580 |
| Model 3 |
0.9550 |
| Model 4 |
0.9379 |
| Average |
0.95185 |
Radius Gyration
|
Similar pdbs
| PDB |
TM-score |
| 2nwi |
0.71211 |
| 4zsi |
0.65741 |
| 4zsk |
0.65722 |
| 3f8l |
0.65127 |
| 2ahc |
0.64951 |
|
Note: The model is built by ab initio method, no significant templates are found!
|
References
[1] Hou, J., Wu, T., Cao, R., & Cheng, J. (2019). Protein tertiary structure modeling driven by deep learning and contact distance prediction in CASP13. bioRxiv, 552422.
[2] Li, J., Deng, X., Eickholt, J., & Cheng, J. (2013). Designing and benchmarking the MULTICOM protein structure prediction system. BMC structural biology, 13(1), 2.
[3] Cheng, J., Li, J., Wang, Z., Eickholt, J., & Deng, X. (2012). The MULTICOM toolbox for protein structure prediction. BMC bioinformatics, 13(1), 65.
[4] Wang, Z., Eickholt, J., & Cheng, J. (2010). MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8. Bioinformatics, 26(7), 882-888.
